Simulation verification techniques study: Simulation performance validation techniques document

Techniques and support software for the efficient performance of simulation validation are discussed. Overall validation software structure, the performance of validation at various levels of simulation integration, guidelines for check case formulation, methods for real time acquisition and formatting of data from an all up operational simulator, and methods and criteria for comparison and evaluation of simulation data are included. Vehicle subsystems modules, module integration, special test requirements, and reference data formats are also described

Simulation verification techniques study. Subsystem simulation validation techniques

Techniques for validation of software modules which simulate spacecraft onboard systems are discussed. An overview of the simulation software hierarchy for a shuttle mission simulator is provided. A set of guidelines for the identification of subsystem/module performance parameters and critical performance parameters are presented. Various sources of reference data to serve as standards of performance for simulation validation are identified. Environment, crew station, vehicle configuration, and vehicle dynamics simulation software are briefly discussed from the point of view of their interfaces with subsystem simulation modules. A detailed presentation of results in the area of vehicle subsystems simulation modules is included. A list of references, conclusions and recommendations are also given

Reliability-Based Electronics Shielding Design Tools

Shielding design on large human-rated systems allows minimization of radiation impact on electronic systems. Shielding design tools require adequate methods for evaluation of design layouts, guiding qualification testing, and adequate follow-up on final design evaluation

Water Quality Hydrology of Lands Receiving Farm Animal Wastes

A significant pollution potential from cattle manure has developed as a result of the cattle feeding industry progressing to large, high density feeding operations. Two major potential sources of pollution from beef feedlots is storm runoff and solid waste (manure). The objectives of this research were to determine the characteristics of storm runoff from a beef feedlot, to determine the nitrogen transformations and ammonia volatilization from soils receiving large manure applications, to determine the chemical quality of surface runoff and groundwater from plots receiving large manure applications, to evaluate techniques of deep plowing large amounts of manure into the soil, and to determine the crop quality and yields on field plots receiving large manure application rates. Feedlot runoff was found to carry large amounts of chemical elements. The concentrations of chemical elements did not vary with size and intensity of rainstorm as much as by differences in topography of the watersheds. More ammonia was volatilized from limed soil columns than unlimed but an unexplained decrease in total nitrogen of 10 to 20 percent occurred in the unlimed and limed soil columns, respectively. A 30-in. moldboard plowing 30 to 36-in. deep can safely turn under up to 900 tons/acre of manure and not create a major surface water pollution problem. An increase of chemical elements in the groundwater occurred during the first year and then were reduced to initial values during the second year. No N03 pollution of groundwater occurred. Crops can be effectively grown on land receiving up to 900 tons/acre of manure. Peak yields will not be obtained the first year after plowing the 900 tons under, but yields will increase the second and third years

Response of Peanuts to Irrigation Management at Different Crop Growth Stages

Past irrigation research on peanuts has shown that when the plant is exposed to soil moisture stress at different crop growth stages, different responses seem to exist between the Spanish and the Florunner peanut varieties. The Spanish peanuts appear more susceptible to soil moisture stress during the blooming and pegging stage, while the Florunners seem more susceptible during the late maturation stage. The objective of this experiment was to determine the optimum irrigation schedule for peanuts at different crop growth stages for the Spanish and the Florunner varieties. The yield of the two varieties was evaluated under seven different irrigation treatments including a "no stress" check treatment and a dryland treatment. Each treatment had a different schedule of either irrigating or stressing the peanut plant during one or more of three crop growth stages. The three crop growth stages were: (1) pegging; (2) early maturation; and (3) late maturation. Rainfall during the vegetative and blooming stage ensured adequate moisture for both of the crop growth stages. Evapotranspiration was monitored throughout the life cycle for both peanut varieties. The evapotranspiration was determined using a soil moisture balance equation. Plant growth in the form of dry matter accumulation and leaf area index was also studied for the Spanish variety. No significant differences in the leaf area index existed between the treatments. The dry matter growth analysis showed that an irrigation during the pegging stage resulted in a faster pod weight accumulation during the early maturation stage than if no irrigation occurred during that stage. The yield and evapotranspiration results showed that differences existed between the two peanut varieties. First, for the Spanish variety, the results indicated that soil moisture is needed during the pegging stage to obtain near maximum yields. Treatments with an irrigation during the pegging stage had a greater evapotranspiration and larger yields, than the treatments without an irrigation during this stage. Second, if an irrigation is made during the pegging stage, an additional irrigation during the early maturation stage is unnecessary. Third, an irrigation during the late maturation stage will increase yield if dry climatic conditions normally exist during this stage. In the case of the Florunner variety, the yield results indicated that moisture stress should occur in no more than one of the crop growth stages if yield reductions are to be minimized. Also, an adequate supply of soil moisture during the late maturation stage is absolutely necessary in order to obtain maximum yields for Florunner peanuts. Treatments which had an irrigation during the late maturation stage had a steady evapotranspiration rate during this crop growth stage and had near maximum yields. Treatments which showed a decrease in the evapotranspiration rate during the late maturation stage produced a significantly lower yield

Arachnida at "Reserva Ducke", Central Amazonia/Brazil

The class Arachnida contains 11 recent orders: Acari, Amblypygi, Araneae, Opiliones, Palpigradi, Pseudoscorpiones, Ricinulei, Schizomida, Scorpiones, Solifugae and Uropygi (Thelyphonida). In total, >570 families, >9165 genera and >93455 species are known world-wide. More than 136 families, >482 genera and >1547 described species occur in Amazonia. Data show, that almost one-fourth of the families presently known in the Arachnida and about 2% of the worlds described species are represented in Amazonia. In the forest reserve 'Reserva Ducke' near Manaus, the Acari-Oribatida represent 45 families, 72 genera and 35 described species, the Aranea 30 families, 143 genera and 295 described species, the Opiliones 5 families, 7 genera and 8 decribed species, the Scorpiones 2 families, 4 genera and 5 described species, the Pseudoscorpiones 6 families, 11 genera, and 15 described species, the Schizomida, 1 family, 2 genera and 2 described species, and the Amblypygi, Palpigradi, Solifugae and Uropygi (Thelyphonida) one species each. Most names are liste

The epidemiology of injuries across the weight-training sports

Background: Weight-training sports, including weightlifting, powerlifting, bodybuilding, strongman, Highland Games, and CrossFit, are weight-training sports that have separate divisions for males and females of a variety of ages, competitive standards, and bodyweight classes. These sports may be considered dangerous because of the heavy loads commonly used in training and competition. Objectives: Our objective was to systematically review the injury epidemiology of these weight-training sports, and, where possible, gain some insight into whether this may be affected by age, sex, competitive standard, and bodyweight class. Methods: We performed an electronic search using PubMed, SPORTDiscus, CINAHL, and Embase for injury epidemiology studies involving competitive athletes in these weight-training sports. Eligible studies included peer-reviewed journal articles only, with no limit placed on date or language of publication. We assessed the risk of bias in all studies using an adaption of the musculoskeletal injury review method. Results: Only five of the 20 eligible studies had a risk of bias score ≥75 %, meaning the risk of bias in these five studies was considered low. While 14 of the studies had sample sizes >100 participants, only four studies utilized a prospective design. Bodybuilding had the lowest injury rates (0.12–0.7 injuries per lifter per year; 0.24–1 injury per 1000 h), with strongman (4.5–6.1 injuries per 1000 h) and Highland Games (7.5 injuries per 1000 h) reporting the highest rates. The shoulder, lower back, knee, elbow, and wrist/hand were generally the most commonly injured anatomical locations; strains, tendinitis, and sprains were the most common injury type. Very few significant differences in any of the injury outcomes were observed as a function of age, sex, competitive standard, or bodyweight class. Conclusion: While the majority of the research we reviewed utilized retrospective designs, the weight-training sports appear to have relatively low rates of injury compared with common team sports. Future weight-training sport injury epidemiology research needs to be improved, particularly in terms of the use of prospective designs, diagnosis of injury, and changes in risk exposure

Determining the Transpiration Rate of Peach Trees Under Two Trickle Irrigation Regimes

The scientific design and management of a modern irrigation system requires that the designer or manager have knowledge of site and plant criteria such as infiltration, drainage, soil fertility, plant water needs, and plant production under varying conditions. With modern trickle systems water control is very precise and thus precise information on irrigation needs of a crop allow for the optimal use of water supplies. Work has been conducted on the effects of trickle irrigation on peach trees in North Central Texas. Initial data relating trickle irrigation amounts to total production, peach size, and plant growth have indicated that trickle irrigation may provide benefits that would offset costs of the irrigation system and water. Previous work however has related these benefits only to the amount of water applied through irrigation and did not consider the total water use of the tree. Research was undertaken to determine the transpiration rate of peach trees under two trickle irrigation regimes. To determine the transpiration rate a volume of soil around the test trees was instrumented with neutron access tubes. Soil moisture depletion was measured weekly. A soil water balance was conducted equating evapotranspiration to the sum of the change in the soil moisture content (a decrease being positive) plus irrigation applied, plus any rainfall that occurred in the period. For this work runoff and flux across the measurement zone boundaries was assumed zero. Estimates of evaporation from the soil surface were made using a two-stage evaporation process along with values of potential evapotranspiration made with the Penman (1956) equation. The estimates of evaporation from the soil surface were subtracted from total evapotranspiration to give estimates of the transpiration of the peach trees. Estimates of transpiration were not consistent from one measurement period to the next. Errors in the estimation of evaporation from the soil surface directly affect the estimate of transpiration. During latter stages of a rain-free period an estimate of transpiration was made which should not have been influences by the low values of evaporation from the soil surface that existed. This method of estimating transpiration has many errors and can be much improved upon by using a method such as a lysimeter to estimate transpiration more accurately

Discovery of the Mexican Blindcat, Prietella phreatophila, in the U.S., and an update on its rangewide conservation status

presented at the 2017 meeting of the Texas Academy of Science at Mary Hardin Baylor University, Belton, TexasMexican blindcat, Prietella phreatophila, was described in 1954 from a single locality in Northern Coahuila, México. Long listed as endangered by the Mexican federal government, it was listed by the U.S. Fish and Wildlife Service as a foreign endangered species in 1970, and the most recent (1996) update of its assessment for the IUCN Red List considers it endangered as well. Explorations in the late 1990s discovered many new localities extending nearly to the international border, and a captive population established provided insights into the species’ basic biology and behavior. In 2016 the species was discovered in a cave in the Amistad National Recreation Area (ANRA), just north of the Río Grande in Texas. The 1970 listing instantly gave the TX population full protection under the U.S. Endangered Species Act. The species’ subterranean and mostly inaccessible habitat endows it with extremely low detectability and its actual range is likely broader than physical sampling of specimens has revealed. We review all prior and new knowledge of the species and its habitat to provide an updated international reassessment of its overall conservation status and threats, which most notably include aquifer depletion and contamination in both the Mexican and U.S. portions of its known range. A live captive population of two specimens collected in 1997 in Coahuila and one Texas specimen is now at the San Antonio Zoo, we are working with NPS to further explore ANRA caves and hope eventually to return to Coahuila to more fully update the species’ conservation status.Integrative Biolog

Novel epoxy-tiglianes stimulate skin keratinocyte wound healing responses and re-epithelialization via protein kinase C activation

Epoxy-tiglianes are a novel class of diterpene esters. The prototype epoxy-tigliane, EBC-46 (tigilanol tiglate), possesses potent anti-cancer properties and is currently in clinical development as a local treatment for human and veterinary cutaneous tumors. EBC-46 rapidly destroys treated tumors and consistently promotes wound re-epithelialization at sites of tumor destruction. However, the mechanisms underlying these keratinocyte wound healing responses are not completely understood. Here, we investigated the effects of EBC-46 and an analogue (EBC-211) at 1.51 nM-151 µM concentrations, on wound healing responses in immortalized human skin keratinocytes (HaCaTs). Both EBC-46 and EBC-211 (1.51 nM-15.1 µM) accelerated G0/G1-S and S-G2/M cell cycle transitions and HaCaT proliferation. EBC-46 (1.51-151 nM) and EBC-211 (1.51 nM-15.1 µM) further induced significant HaCaT migration and scratch wound repopulation. Stimulated migration/wound repopulation responses were even induced by EBC-46 (1.51 nM) and EBC-211 (1.51-151 nM) with proliferation inhibitor, mitomycin C (1 μM), suggesting that epoxy-tiglianes can promote migration and wound repopulation independently of proliferation. Expression profiling analyses showed that epoxytiglianes modulated keratin, DNA synthesis/replication, cell cycle/proliferation, motility/migration, differentiation, matrix metalloproteinase (MMP) and cytokine/chemokine gene expression, to facilitate enhanced responses. Although epoxy-tiglianes down-regulated established cytokine and chemokine agonists of keratinocyte proliferation and migration, enhanced HaCaT responses were demonstrated to be mediated via protein kinase C (PKC) phosphorylation and significantly abrogated by pan-PKC inhibitor, bisindolylmaleimide-1 (BIM-1, 1 μM). By identifying how epoxy-tiglianes stimulate keratinocyte healing responses and re-epithelialization in treated skin, our findings support the further development of this class of small molecules as potential therapeutics for other clinical situations associated with impaired re-epithelialization, such as non-healing skin wounds